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Decreased IgD- CD27- double negative B cells in Sjögren’s disease correlated with disease activity index

Abstract Double negative (DN) B cells, defined as CD27-IgD- B cells, are increased in older healthy individuals as well as in patients with certain diseases. However, the relationship between DN B cells and Sjögren’s disease (SjD) in newly diagnosed patients remains unclear. Seventy SjD patients and...

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Autors principals: Lin Zhao, Jing Yang, Changyan Liu, Mingxi Xu, Yida Xing, Xiaodan Kong
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2025-10-01
Col·lecció:Scientific Reports
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Accés en línia:https://doi.org/10.1038/s41598-025-19796-9
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