Sugarcane Polyphenols Improve Depressive-like Behavior in CUMS Mice by Promoting the MAPK/ERK Signaling Pathway and Inhibiting NLRP3 Inflammasome Pyroptosis

Sugarcane polyphenols (SP) are investigated for their antidepressant potential using a CUMS-induced mouse model and a corticosterone-induced neuronal injury cell model. Results demonstrate that SP alleviates depressive-like behaviors, inhibits hippocampal neuronal apoptosis, and reduces neuroinflamm...

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Autori principali:	Xue Wang, Jiapeng Song, Zhongmei He, Jianming Li, Yan Zhao, Ying Zong, Jianan Geng, Jia Zhou, Junkoo Yi, Weijia Chen, Rui Du
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2026-06-01
Serie:	Foods
Soggetti:	sugarcane polyphenols (SP) depression MAPK NLRP3 inflammasome pyroptosis
Accesso online:	https://www.mdpi.com/2304-8158/15/13/2322
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