Structure and functional implications of WYL domain-containing bacterial DNA damage response regulator PafBC
The transcriptional activator PafBC is a regulator of mycobacterial DNA damage response and upregulates genes involved in DNA repair. Here, the authors present the crystal structure of Arthrobacter aurescens PafBC and suggest that PafBC might be activated by binding of a nucleic acid ligand, and bio...
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| Principais autores: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2019-10-01
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| Serier: | Nature Communications |
| Online adgang: | https://doi.org/10.1038/s41467-019-12567-x |
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