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Pharmacological evidence for lithium-induced neuroprotection against methamphetamine-induced neurodegeneration via Akt-1/GSK3 and CREB-BDNF signaling pathways

Objective(s): Neurodegeneration is an outcome of Methamphetamine (METH) abuse. Studies have emphasized on the neuroprotective properties of lithium. The current study is designed towards evaluating the role of Akt-1/GSK3 and CREB-BDNF signaling pathways in mediating lithium neuroprotection against M...

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Principais autores: Shafagh Mehrafza, Sareh Kermanshai, Shahnaz Mostafidi, Majid Motaghinejad, Manijeh Motevalian, Sulail Fatima
Format: Artigo
Sprog:Inglês
Udgivet: Mashhad University of Medical Sciences 2019-08-01
Serier:Iranian Journal of Basic Medical Sciences
Fag:
Akt
BDNF
CREB
Lithium
Methamphetamine
GSK3
Online adgang:http://ijbms.mums.ac.ir/article_13235_879af5783039013a2cbc3b40dc57e1ad.pdf
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