Co-vulnerabilities of inhibiting carbonic anhydrase IX in ferroptosis-mediated tumor cell death
The tumour-associated carbonic anhydrases (CA) IX and XII are upregulated by cancer cells to combat cellular and metabolic stress imparted by hypoxia and acidosis in solid tumours. Owing to its tumour-specific expression and function, CAIX is an attractive therapeutic target and this has driven inte...
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| Hoofdauteurs: | , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Frontiers Media S.A.
2023-11-01
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| Reeks: | Frontiers in Molecular Biosciences |
| Onderwerpen: | |
| Online toegang: | https://www.frontiersin.org/articles/10.3389/fmolb.2023.1327310/full |
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