Together JUN and DDIT3 (CHOP) control retinal ganglion cell death after axonal injury

Abstract Background Optic nerve injury is an important pathological component in neurodegenerative diseases such as traumatic optic neuropathies and glaucoma. The molecular signaling pathway(s) critical for retinal ganglion cell (RGC) death after axonal insult, however, is/are not fully defined. RGC...

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Principais autores:	Stephanie B. Syc-Mazurek, Kimberly A. Fernandes, Michael P. Wilson, Peter Shrager, Richard T. Libby
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2017-10-01
Serija:	Molecular Neurodegeneration
Teme:	Axonopathy Neurodegeneration Retinal ganglion cell Mitogen-activated protein kinase Endoplasmic reticulum stress
Online dostop:	http://link.springer.com/article/10.1186/s13024-017-0214-8
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