β-Hydroxybutyrate impairs neutrophil migration distance through activation of a protein kinase C and myosin light chain 2 signaling pathway in ketotic cows

ABSTRACT: Ketosis in dairy cows often occurs in the peripartal period and is accompanied by immune dysfunction. High concentrations of β-hydroxybutyrate (BHB) in peripheral blood during ketosis are closely related to the impairment of polymorphonuclear neutrophil (PMN) chemotaxis and contribute to i...

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Bibliografische Detailangaben

Hauptverfasser:	Yuxiang Song, Yuchen Yang, Wen Zeng, Juan J. Loor, Qianming Jiang, Zhicheng Peng, Yunfei Li, Shang Jiang, Xiancheng Feng, Xiliang Du, Xinwei Li, Guowen Liu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2022-01-01
Schriftenreihe:	Journal of Dairy Science
Schlagworte:	ketosis immune dysfunction β-hydroxybutyrate polymorphonuclear neutrophil migration distance
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S0022030221009498
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