Bioinformatic prediction of the stereoselectivity of modular polyketide synthase: an update of the sequence motifs in ketoreductase domain
Polyketides are a major class of natural products, including bioactive medicines such as erythromycin and rapamycin. They are often rich in stereocenters biosynthesized by the ketoreductase (KR) domain within the polyketide synthase (PKS) assembly line. Previous studies have identified conserved mot...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Beilstein-Institut
2024-07-01
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| Col·lecció: | Beilstein Journal of Organic Chemistry |
| Matèries: | |
| Accés en línia: | https://doi.org/10.3762/bjoc.20.131 |
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