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Depletion of cellular iron by curcumin leads to alteration in histone acetylation and degradation of Sml1p in Saccharomyces cerevisiae.

Curcumin, a naturally occurring polyphenolic compound, is known to possess diverse pharmacological properties. There is a scarcity of literature documenting the exact mechanism by which curcumin modulates its biological effects. In the present study, we have used yeast as a model organism to dissect...

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Główni autorzy: Gajendra Kumar Azad, Vikash Singh, Upendarrao Golla, Raghuvir S Tomar
Format: Artigo
Język:Inglês
Wydane: Public Library of Science (PLoS) 2013-01-01
Seria:PLoS ONE
Dostęp online:http://europepmc.org/articles/PMC3592818?pdf=render
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