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Decoding chronic pain: the glutamate-GABA tug of war in the cerebral cortex

A sustained imbalance between excitatory and inhibitory mechanisms within the glutamatergic and GABAergic systems of the cerebral cortex, induced by noxious stimuli, is a fundamental characteristic in the development and maintenance of chronic pain. This review provides a comprehensive summary of th...

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Kaydedildi:
Asıl Yazarlar: Dan Huang, Yu-Ting Dong, Liu-Xuan He, Rui-Zhu Zhou, Jian-Xiong Zhou, Sha Yang, Shu-Guang Yu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2025-07-01
Seri Bilgileri:Frontiers in Molecular Neuroscience
Konular:
chronic pain
cerebral cortex
glutamatergic system
GABAergic system
neural network
Online Erişim:https://www.frontiersin.org/articles/10.3389/fnmol.2025.1572775/full
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