HLA class I-naturally presented synovial tissue peptides are recognized by CD8+ T lymphocytes from rheumatoid arthritis patients

IntroductionRheumatoid arthritis (RA) is an autoimmune disease resulting from a response driven by self-reactive CD4+ T cells that recognize autoantigenic peptides presented by antigen-presenting cells (APCs). Recent evidence suggests that CD8+ T cells are also important players in this process. Thi...

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Principais autores:	Diego Catalán, Daniela Schneider, Bárbara Pesce, Miqueas Jaime, Lucero Toro, Constanza Varela-Villarroel, Darly Montano-Bruno, Lilian Soto, Francisca Bozán, María Carolina Cuéllar-Gutiérrez, Óscar Neira, Consuelo Arroyo, Guido Rivera, Milton Larrondo, Jaime Hinzpeter, Montserrat Carrascal, Juan C. Aguillón, Jaxaira Maggi
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2026-07-01
סדרה:	Frontiers in Immunology
נושאים:	autoantigens CD8+ T cells HLA class I immunopeptidomics rheumatoid arthritis
גישה מקוונת:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1843318/full
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