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The Small Molecule PPARγ Agonist GL516 Induces Feeding-Stimulatory Effects in Hypothalamus Cells Hypo-E22 and Isolated Hypothalami

PPARγ agonists are implicated in the regulation of diabetes and metabolic syndrome and have therapeutic potential in brain disorders. PPARγ modulates appetite through its central effects, especially on the hypothalamic arcuate nucleus (ARC). Previous studies demonstrated that the small molecule GL51...

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Principais autores: Annalisa Chiavaroli, Viviana di Giacomo, Barbara De Filippis, Amelia Cataldi, Claudio Ferrante, Letizia Giampietro
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2022-07-01
סדרה:Molecules
נושאים:
PPARγ agonists
fibrates
neuroprotection
hypothalamus
small molecules
neuropeptides
גישה מקוונת:https://www.mdpi.com/1420-3049/27/15/4882
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