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Biological characteristics of transcription factor RelB in different immune cell types: implications for the treatment of multiple sclerosis

Abstract Transcription factor RelB is a member of the nuclear factror-kappa B (NF-κB) family, which plays a crucial role in mediating immune responses. Plenty of studies have demonstrated that RelB actively contributes to lymphoid organ development, dendritic cells maturation and function and T cell...

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Principais autores: Meng-ge Yang, Li Sun, Jinming Han, Chao Zheng, Hudong Liang, Jie Zhu, Tao Jin
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2019-12-01
Serier:Molecular Brain
Fag:
RelB
NF-κB
Multiple sclerosis
Experimental autoimmune encephalomyelitis
Neuroinflammation
Online adgang:https://doi.org/10.1186/s13041-019-0532-6
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