A clinically relevant large‐scale biomanufacturing workflow to produce natural killer cells and natural killer cell‐derived extracellular vesicles for cancer immunotherapy

Abstract Natural killer cell‐derived extracellular vesicles (NK‐EVs) have shown promising potential as biotherapeutics for cancer due to their unique attributes as cytotoxic nanovesicles against cancer cells and immune‐modulatory activity towards immune cells. However, a biomanufacturing workflow is...

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Autori principali:	Frederic St‐Denis‐Bissonnette, Sarah E. Cummings, Shirley Qiu, Andrew Stalker, Gauri Muradia, Jelica Mehic, Karan Mediratta, Shelby Kaczmarek, Dylan Burger, Seung‐Hwan Lee, Lisheng Wang, Jessie R. Lavoie
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2023-12-01
Serie:	Journal of Extracellular Vesicles
Soggetti:	biomanufacturing workflow cancer immunotherapy clinical‐grade extracellular vesicles (EVs) natural killer (NK) cells scalable production
Accesso online:	https://doi.org/10.1002/jev2.12387
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