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Apico-basal cell compression regulates Lamin A/C levels in epithelial tissues

The nuclear lamina bridges mechanical forces from the cytoskeleton to the nucleus, and while Lamin A/C is known to be crucial for this process, its regulation remains unclear. Here the authors show that levels of Lamin A/C scale with apico-basal compression of cells independently of tissue stiffness...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: K. Venkatesan Iyer, Anna Taubenberger, Salma Ahmed Zeidan, Natalie A. Dye, Suzanne Eaton, Frank Jülicher
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Nature Portfolio 2021-03-01
Rangatū:Nature Communications
Urunga tuihono:https://doi.org/10.1038/s41467-021-22010-9
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