SNORD60-mediated 2′-O-methylation of KCP enhances ferroptosis sensitivity in hepatoblastoma

Abstract Ferroptosis has increasingly emerged as a novel target for cancer therapy because of intrinsic or acquired ferroptosis vulnerabilities in cancers. Small nucleolar RNA (snoRNA)-mediated mRNA modifications play a critical role in regulating ferroptosis and supporting tumor cell adaptation. Ho...

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Principais autores:	Jiabei Zhu, Wenxuan Ni, Zhixuan Bian, Yixuan Xiao, Jing Xiao, Hongwen Zhu, Ni Zhen, Qi Zhang, Cizhong Jiang, Ji Ma, Fenyong Sun, Qiuhui Pan
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Publishing Group 2026-05-01
Serija:	Cell Death Discovery
Online dostop:	https://doi.org/10.1038/s41420-026-03160-5
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