Mechanisms Underlying Gastrodin Alleviating Vincristine-Induced Peripheral Neuropathic Pain

Gastrodin (GAS) is the main bioactive ingredient of Gastrodia, a famous Chinese herbal medicine widely used as an analgesic, but the underlying analgesic mechanism is still unclear. In this study, we first observed the effects of GAS on the vincristine-induced peripheral neuropathic pain by alleviat...

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Hlavní autoři:	Xiangyu Wang, Boxuan Zhang, Xuedong Li, Xingang Liu, Songsong Wang, Yuan Xie, Jialing Pi, Zhiyuan Yang, Jincan Li, Qingzhong Jia, Yang Zhang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2021-12-01
Edice:	Frontiers in Pharmacology
Témata:	NaV1.7/NaV1.8 vincristine neuropathic pain molecular docking MD simulation gastrodin
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fphar.2021.744663/full
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