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Synthesis, Stability, and Antidiabetic Activity Evaluation of (−)-Epigallocatechin Gallate (EGCG) Palmitate Derived from Natural Tea Polyphenols

This work describes a novel approach for the synthesis of (−)-epigallocatechin gallate (EGCG) palmitate by a chemical-synthesis method, where the elevated stability of the EGCG derivative is achieved. Various parameters affecting the acylation process, such as the base, solvent, as well as the molar...

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Main Authors: Bingbing Liu, Zhengzhong Kang, Weidong Yan
Format: Artigo
Language:Inglês
Published: MDPI AG 2021-01-01
Series:Molecules
Subjects:
EGCG palmitate
molecular modification
stability
antidiabetic activity
molecular docking
Online Access:https://www.mdpi.com/1420-3049/26/2/393
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