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Structural and ensemble-based mechanistic insights into cytoplasmic dynein-1

Cytoplasmic dynein-1 is a multi-subunit motor that transports diverse cargoes toward microtubule minus-ends, playing crucial roles in intracellular organisation and cell division. Over the past decade, X-ray crystallography and cryo-EM approaches have captured numerous high-resolution structures of...

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Autor principal: Amit Kumawat
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2026-05-01
Col·lecció:Frontiers in Molecular Biosciences
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fmolb.2026.1832580/full
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