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Genetically-predicted life-long lowering of low-density lipoprotein cholesterol is associated with decreased frailty: A Mendelian randomization study in UK biobankResearch in context

Background: High circulating low-density lipoprotein cholesterol (LDL-C) is a major risk factor for atherosclerosis and age-associated cardiovascular events. Long-term dyslipidaemia could contribute to the development of frailty in older individuals through its role in determining cardiovascular hea...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Qi Wang, Yunzhang Wang, Kelli Lehto, Nancy L. Pedersen, Dylan M. Williams, Sara Hägg
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2019-07-01
Rangatū:EBioMedicine
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2352396419304426
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