Exosomes released by hepatocarcinoma cells endow adipocytes with tumor-promoting properties

Abstract Background The initiation and progression of hepatocellular carcinoma (HCC) are largely dependent on its local microenvironment. Adipocytes are an important component of hepatic microenvironment in nonalcoholic fatty liver disease (NAFLD), which is a significant risk factor for HCC. Given t...

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Detalhes bibliográficos

Principais autores:	Shihua Wang, Meiqian Xu, Xiaoxia Li, Xiaodong Su, Xian Xiao, Armand Keating, Robert Chunhua Zhao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2018-06-01
Colecção:	Journal of Hematology & Oncology
Assuntos:	Exosomes Adipocyte HCC MSCs NF-κB
Acesso em linha:	http://link.springer.com/article/10.1186/s13045-018-0625-1
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