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Harnessing Neutrophil Survival Mechanisms during Chronic Infection by Pseudomonas aeruginosa: Novel Therapeutic Targets to Dampen Inflammation in Cystic Fibrosis

More than two decades after cloning the cystic fibrosis transmembrane regulator (CFTR) gene, the defective gene in cystic fibrosis (CF), we still do not understand how dysfunction of this ion channel causes lung disease and the tremendous neutrophil burden which persists within the airways; nor why...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Benoît S. Marteyn, Pierre-Régis Burgel, Laurent Meijer, Véronique Witko-Sarsat
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Frontiers Media S.A. 2017-06-01
Цуврал:Frontiers in Cellular and Infection Microbiology
Нөхцлүүд:
Онлайн хандалт:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00243/full
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