Imeglimin improves hyperglycemia and hypoglycemia‐induced cell death and mitochondrial dysfunction in immortalized adult mouse Schwann IMS32 cells

ABSTRACT Aims/Introduction Imeglimin, a novel oral antidiabetic drug, enhances glucose‐stimulated insulin secretion, improves insulin sensitivity, and reduces mitochondrial reactive oxygen species (ROS) generation. Diabetic neuropathy is driven by oxidative stress caused by hyperglycemia, with mitoc...

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Detalhes bibliográficos

Principais autores:	Ayako Kato, Wataru Nihei, Hideji Yako, Yasuaki Tatsumi, Tatsuhito Himeno, Masaki Kondo, Yoshiro Kato, Jiro Nakamura, Hideki Kamiya, Kazunori Sango, Koichi Kato
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2025-09-01
coleção:	Journal of Diabetes Investigation
Assuntos:	Diabetic neuropathy Mitochondria Schwann cells
Acesso em linha:	https://doi.org/10.1111/jdi.70092
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