Spatial Organization and Recruitment of Non-Specific T Cells May Limit T Cell-Macrophage Interactions Within Mycobacterium tuberculosis Granulomas

Tuberculosis (TB) is a worldwide health problem; successful interventions such as vaccines and treatment require a 2better understanding of the immune response to infection with Mycobacterium tuberculosis (Mtb). In many infectious diseases, pathogen-specific T cells that are recruited to infection s...

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Autori principali:	Jess A. Millar, J. Russell Butler, Stephanie Evans, Nicole L. Grant, Joshua T. Mattila, Jennifer J. Linderman, JoAnne L. Flynn, Denise E. Kirschner
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2021-01-01
Serie:	Frontiers in Immunology
Soggetti:	T cell macrophage Mycobacterium tuberculosis lung computational model granuloma
Accesso online:	https://www.frontiersin.org/articles/10.3389/fimmu.2020.613638/full
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