Inhibition of MurA Enzyme from <i>Escherichia coli</i> and <i>Staphylococcus aureus</i> by Diterpenes from <i>Lepechinia meyenii</i> and Their Synthetic Analogs

Enzymes MurA and MurF, involved in bacterial cell wall synthesis, have been validated as targets for the discovery of novel antibiotics. A panel of plant-origin antibacterial diterpenes and synthetic analogs derived therefrom were investigated for their inhibitory properties on these enzymes from <i...

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Principais autores:	Macarena Funes Chabán, Martina Hrast, Rok Frlan, Dafni G. Graikioti, Constantinos M. Athanassopoulos, María Cecilia Carpinella
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-12-01
coleção:	Antibiotics
Assuntos:	dehydroabietane derivatives diterpenes MurA and MurF inhibitors <i>Staphylococcus aureus</i> MurA <i>Escherichia coli</i> MurA
Acesso em linha:	https://www.mdpi.com/2079-6382/10/12/1535
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