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Reduced matrix rigidity promotes neonatal cardiomyocyte dedifferentiation, proliferation and clonal expansion

Cardiomyocyte (CM) maturation in mammals is accompanied by a sharp decline in their proliferative and regenerative potential shortly after birth. In this study, we explored the role of the mechanical properties of the underlying matrix in the regulation of CM maturation. We show that rat and mouse n...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Yfat Yahalom-Ronen, Dana Rajchman, Rachel Sarig, Benjamin Geiger, Eldad Tzahor
Hōputu: Artigo
Reo:Inglês
I whakaputaina: eLife Sciences Publications Ltd 2015-08-01
Rangatū:eLife
Ngā marau:
Urunga tuihono:https://elifesciences.org/articles/07455
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