Dynamic Malignant Wave of Ribosome-Insulted Gut Niche via the Wnt-CTGF/CCN2 Circuit

Summary: Stress-driven ribosome dysfunction triggers an eIF2α-mediated integrated stress response to maintain cellular homeostasis. Among four key eIF2α kinases, protein kinase R (PKR) expression positively associates with poor prognoses for colorectal cancer (CRC) patients. We identified PKR-linked...

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Detalles Bibliográficos

Autores principales:	Ki Hyung Kim, Seung Joon Lee, Juil Kim, Yuseok Moon
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2020-05-01
Colección:	iScience
Materias:	Biological Sciences Cell Biology Functional Aspects of Cell Biology Cancer
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S2589004220302613
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