LncRNA Hnf4αos exacerbates liver ischemia/reperfusion injury in mice via Hnf4αos/Hnf4α duplex-mediated PGC1α suppression

LncRNAs are involved in the pathophysiologic processes of multiple diseases, but little is known about their functions in hepatic ischemia/reperfusion injury (HIRI). As a novel lncRNA, the pathogenetic significance of hepatic nuclear factor 4 alpha, opposite strand (Hnf4αos) in hepatic I/R injury re...

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Autori principali:	Chaoqun Wang, Hongjun Yu, Shounan Lu, Shanjia Ke, Yanan Xu, Zhigang Feng, Baolin Qian, Miaoyu Bai, Bing Yin, Xinglong Li, Yongliang Hua, Liqian Dong, Yao Li, Bao Zhang, Zhongyu Li, Dong Chen, Bangliang Chen, Yongzhi Zhou, Shangha Pan, Yao Fu, Hongchi Jiang, Dawei Wang, Yong Ma
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2022-11-01
Serie:	Redox Biology
Soggetti:	Hnf4αos Liver Ischemia/reperfusion PGC1α Reactive oxygen species
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2213231722002701
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