Population pharmacokinetics of remlifanserin (ACP‐204), a serotonin 2A receptor inverse agonist

Abstract INTRODUCTION Remlifanserin, or ACP‐204, is a potent serotonin 2A receptor inverse agonist under investigation for treatment of Alzheimer's disease psychosis and Lewy body dementia psychosis. A population pharmacokinetics (popPK) model for remlifanserin was developed to evaluate the impact o...

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Autori principali:	Mona Darwish, Nancy Lin, Bryan Dirks, David Jaworowicz, Kelly Maxwell, Sanjeev Pathak
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2026-04-01
Serie:	Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Soggetti:	5‐HT2A receptor inverse agonist ACP‐204 Alzheimer's disease dementia Lewy body dementia model evaluation
Accesso online:	https://doi.org/10.1002/trc2.70254
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