Thalidomide and Phosphodiesterase 4 Inhibitors as Host Directed Therapeutics for Tuberculous Meningitis: Insights From the Rabbit Model

Tuberculous meningitis (TBM) is the most devastating form of extrapulmonary Mycobacterium tuberculosis infection in humans. Severe inflammation and extensive tissue damage drive the morbidity and mortality of this manifestation of tuberculosis (TB). Antibiotic treatment is ineffective at curing TBM...

Descrición completa

Detalles Bibliográficos

Principais autores:	Ranjeet Kumar, Afsal Kolloli, Pooja Singh, Christopher Vinnard, Gilla Kaplan, Selvakumar Subbian
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2020-01-01
Series:	Frontiers in Cellular and Infection Microbiology
Assuntos:	tuberculosis mycobacterium cerebrospinal fluid phosphodiesterase-4 inhibitors inflammation corticosteroid
Acceso en liña:	https://www.frontiersin.org/article/10.3389/fcimb.2019.00450/full
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!