A role for IL-33–activated ILC2s in eosinophilic vasculitis
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare but serious disease with poorly understood mechanisms. Here, we report that patients with EGPA have elevated levels of TSLP, IL-25, and soluble ST2, which are well-characterized cytokine “alarmins” that activate or modulate type 2 innate...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Clinical investigation
2021-06-01
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| Seri Bilgileri: | JCI Insight |
| Konular: | |
| Online Erişim: | https://doi.org/10.1172/jci.insight.143366 |
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