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An Emerging Role for IQGAP1 in Regulating Protein Traffic

IQGAP1, an effector of CDC42p GTPase, is a widely conserved, multifunctional protein that bundles F-actin through its N-terminus and binds microtubules through its C-terminus to modulate the cell architecture. It has emerged as a potential oncogene associated with diverse human cancers. Therefore, I...

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Auteur principal: Mahasin Osman
Format: Artigo
Langue:Inglês
Publié: Wiley 2010-01-01
Collection:The Scientific World Journal
Accès en ligne:http://dx.doi.org/10.1100/tsw.2010.85
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