Clinical and brain volumetric correlates of decreased DTI-ALPS, suggestive of local glymphatic dysfunction, in iRBD

Abstract Glymphatic alterations may underlie neurodegeneration in alpha-synucleinopathies. Reduced Diffusion-Tensor Imaging ALong the Perivascular Space (DTI-ALPS), a proxy of perivascular glymphatic activity, has been scarcely studied in isolated REM sleep behaviour disorder (iRBD), a prodromal syn...

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Bibliografiske detaljer

Principais autores:	Ignacio Roura, Jèssica Pardo, Cristina Martín-Barceló, Carles Falcon, Javier Oltra, Anna Campabadal, Nuria Bargalló, Mònica Serradell, Gerard Mayà, Angelica Montini, Claustre Pont-Sunyer, Carles Gaig, Mariateresa Buongiorno, Carme Junqué, Alex Iranzo, Bàrbara Segura
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2025-04-01
Serier:	npj Parkinson's Disease
Online adgang:	https://doi.org/10.1038/s41531-025-00942-z
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