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Individual globular domains and domain unfolding visualized in overstretched titin molecules with atomic force microscopy.

Titin is a giant elastomeric protein responsible for the generation of passive muscle force. Mechanical force unfolds titin's globular domains, but the exact structure of the overstretched titin molecule is not known. Here we analyzed, by using high-resolution atomic force microscopy, the structure...

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Auteurs principaux: Zsolt Mártonfalvi, Miklós Kellermayer
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2014-01-01
Collection:PLoS ONE
Accès en ligne:http://europepmc.org/articles/PMC3896421?pdf=render
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