Synthesis of triazolo- and tetrazolo-fused 1,4-benzodiazepines via one-pot Ugi–azide and Cu-free click reactions

A one-pot Ugi–azide reaction followed by intramolecular Cu-free azide–alkyne cycloaddition generates a polycyclic scaffold 7 bearing polycyclic triazole, tetrazole, and benzodiazepine rings. This method could be extended for obtaining a more complicated scaffold 8 containing a piperazinone ring.

Dades bibliogràfiques

Autors principals:	Xiaoming Ma, Zijie Gao, Jiawei Niu, Wentao Shao, Shenghu Yan, Sai Zhang, Wei Zhang
Format:	Artigo
Idioma:	Inglês
Publicat:	Beilstein-Institut 2025-10-01
Col·lecció:	Beilstein Journal of Organic Chemistry
Matèries:	benzodiazepine click reaction multicomponent reaction one-pot piperazinone polycyclic triazole tetrazole ugi–azide reaction
Accés en línia:	https://doi.org/10.3762/bjoc.21.167
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!