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A Question of Frame: The Role of the Bone Marrow Stromal Niche in Myeloid Malignancies

Until a few years ago, the onset of acute myeloid leukemia (AML) was entirely ascribed to genetic lesions in hematopoietic stem cells. These mutations generate leukemic stem cells, which are known to be the main ones responsible for chemoresistance and relapse. However, in the last years, increasing...

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Principais autores: Chiara Tomasoni, Alice Pievani, Benedetta Rambaldi, Andrea Biondi, Marta Serafini
Format: Artigo
Jezik:Inglês
Izdano: Wiley 2023-06-01
Serija:HemaSphere
Online dostop:http://journals.lww.com/10.1097/HS9.0000000000000896
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