Hippocampal neurons isolated from rats subjected to the valproic acid model mimic in vivo synaptic pattern: evidence of neuronal priming during early development in autism spectrum disorders

Abstract Background Autism spectrum disorders (ASD) are synaptopathies characterized by area-specific synaptic alterations and neuroinflammation. Structural and adhesive features of hippocampal synapses have been described in the valproic acid (VPA) model. However, neuronal and microglial contributi...

Whakaahuatanga katoa

Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Marianela Evelyn Traetta, Martín Gabriel Codagnone, Nonthué Alejandra Uccelli, Alberto Javier Ramos, Sandra Zárate, Analía Reinés
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	BMC 2021-03-01
Rangatū:	Molecular Autism
Ngā marau:	Autism spectrum disorders VPA model Synapse NCAM Hippocampus Adhesion molecules
Urunga tuihono:	https://doi.org/10.1186/s13229-021-00428-8
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!