Enhancing radiotherapy response via intratumoral injection of a TLR9 agonist in autochthonous murine sarcomas

Radiation therapy (RT) is frequently used to treat cancers, including soft-tissue sarcomas. Prior studies established that the toll-like receptor 9 (TLR9) agonist cytosine-phosphate-guanine oligodeoxynucleotide (CpG) enhances the response to RT in transplanted tumors, but the mechanisms of this enha...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Chang Su, Collin L. Kent, Matthew Pierpoint, Warren Floyd, Lixia Luo, Nerissa T. Williams, Yan Ma, Brian Peng, Alexander L. Lazarides, Ajay Subramanian, Jonathon E. Himes, Vincent M. Perez, Rosa D. Hernansaiz-Ballesteros, Kimberly E. Roche, Jennifer L. Modliszewski, Sara R. Selitsky, Mari L. Shinohara, Amy J. Wisdom, Everett J. Moding, Yvonne M. Mowery, David G. Kirsch
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical investigation 2024-07-01
Serie:	JCI Insight
Soggetti:	Immunology Oncology
Accesso online:	https://doi.org/10.1172/jci.insight.178767
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!