A Multicenter, Double‐Blind, Placebo‐Controlled, Randomized Clinical Trial of Oral Anticoagulation in Systemic Sclerosis‐Related Pulmonary Arterial Hypertension—Results From the SPHInX Study

ABSTRACT The SPHInX study is the first‐ever randomized controlled trial (RCT) seeking to inform an area of equipoise regarding the efficacy of oral anticoagulation as adjunct therapy in systemic sclerosis‐related pulmonary arterial hypertension (SSc‐PAH). The SPHInX study was an Australian multicent...

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Autores principales:	Mandana Nikpour, Alicia Calderone, Susanna M. Proudman, Dylan Hansen, Eli Gabbay, Nathan Dwyer, Gregory Keir, Vivek Thakkar, Peter K. K. Wong, Anne Keogh, Andrew Burns, David Prior, Harshal Nandurkar, David S. Celermajer, Joanne Sahhar, Rachelle Buchbinder, Wendy Stevens
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Wiley 2026-04-01
Colección:	Pulmonary Circulation
Materias:	autoimmune connective tissue disease therapeutics
Acceso en línea:	https://doi.org/10.1002/pul2.70331
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