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miR-424/322 attenuates cardiac remodeling by modulating the nuclear factor-activated T-cell 3/furin pathway

Background: Cardiac remodeling is implicated in numerous physiologic and pathologic conditions, including scar formation, heart failure, and cardiac arrhythmias. Nuclear factor-activated T-cell cytoplasmic (NFATc) is a crucial transcription factor that regulates cardiac remodeling. MicroRNA (miR)-42...

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Principais autores: Hsiao-Ya Tsai, Jen-Chun Wang, Yu-Juei Hsu, Chih-Yuan Lin, Po-Hsun Huang, Min-Chien Tsai, Chin-Wang Hsu, Shang-Feng Yang, Shih-Hung Tsai
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2025-08-01
Serier:Biomedical Journal
Fag:
Nuclear factor-activated T cell
Furin
miR-424/322
Hypertrophy
Cardiac remodeling
Angiotensin II
Online adgang:http://www.sciencedirect.com/science/article/pii/S2319417024001215
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