Enhanced renal clearance impacts levetiracetam concentrations in patients with traumatic brain injury with and without augmented renal clearance

Abstract Background The purpose of this study was to examine the impact of ARC on levetiracetam concentrations during the first week following acute TBI. The hypothesis was levetiracetam concentrations are significantly lower in TBI patients with augmented renal clearance (ARC) compared to those wit...

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Principais autores:	Aaron M. Cook, Kaylee Hall, Jimmi Hatton Kolpek, Kathryn A. Morbitzer, J. Dedrick Jordan, Denise H. Rhoney
格式:	Artigo
語言:	Inglês
出版:	BMC 2024-01-01
叢編:	BMC Neurology
主題:	Augmented renal clearance Creatinine clearance Traumatic brain injury Pharmacokinetics Levetiracetam Seizure prophylaxis
在線閱讀:	https://doi.org/10.1186/s12883-023-03515-w
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