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CD44-targeted pH-responsive micelles for enhanced cellular internalization and intracellular on-demand release of doxorubicin

Poor cellular uptake and slow intracellular drug release remain the main barriers for the efficient application of micellar delivery system. Taking advantage of the overexpressed CD44 receptor and mild acidic microenvironment of tumour cells, CD44-targeted pH-responsive micelles based on the self-as...

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Detalhes bibliográficos
Principais autores: Shudi Yang, Weiliang Chen, Wei Li, Jingcheng Song, Yue Gao, Xiaoping Li
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2021-01-01
coleção:Artificial Cells, Nanomedicine, and Biotechnology
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Acesso em linha:https://www.tandfonline.com/doi/10.1080/21691401.2021.1884085
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