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Altered Frequencies and Functions of Innate Lymphoid Cells in Melanoma Patients Are Modulated by Immune Checkpoints Inhibitors

Monoclonal antibodies targeting immune checkpoints improved clinical outcome of patients with malignant melanoma. However, the mechanisms are not fully elucidated. Since immune check-point receptors are also expressed by helper innate lymphoid cells (ILCs), we investigated the capability of immune c...

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Hoofdauteurs: Costanza Maria Cristiani, Mariaelena Capone, Cinzia Garofalo, Gabriele Madonna, Domenico Mallardo, Marilena Tuffanelli, Vito Vanella, Marta Greco, Daniela Patrizia Foti, Giuseppe Viglietto, Paolo Antonio Ascierto, Hergen Spits, Ennio Carbone
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2022-01-01
Reeks:Frontiers in Immunology
Onderwerpen:
innate lymphoid cells
cytokines
melanoma
immune checkpoints inhibitors
nivolumab
Online toegang:https://www.frontiersin.org/articles/10.3389/fimmu.2022.811131/full
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