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Targeted deletion of the aquaglyceroporin AQP9 is protective in a mouse model of Parkinson's disease.

More than 90% of the cases of Parkinson's disease have unknown etiology. Gradual loss of dopaminergic neurons of substantia nigra is the main cause of morbidity in this disease. External factors such as environmental toxins are believed to play a role in the cell loss, although the cause of the sele...

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Autori principali: Katja Stahl, Soulmaz Rahmani, Agnete Prydz, Nadia Skauli, Nanna MacAulay, Maria N Mylonakou, Reidun Torp, Øivind Skare, Torill Berg, Trygve B Leergaard, Ragnhild E Paulsen, Ole P Ottersen, Mahmood Amiry-Moghaddam
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2018-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC5864064?pdf=render
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