Identification of a Novel Therapeutic Target against XDR <i>Salmonella</i> Typhi H58 Using Genomics Driven Approach Followed Up by Natural Products Virtual Screening

Typhoid fever is caused by a pathogenic, rod-shaped, flagellated, and Gram-negative bacterium known as <i>Salmonella</i> Typhi. It features a polysaccharide capsule that acts as a virulence factor and deceives the host immune system by protecting phagocytosis. Typhoid fever remains a major health co...

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Detalhes bibliográficos

Principais autores:	Khurshid Jalal, Kanwal Khan, Muhammad Hassam, Muhammad Naseer Abbas, Reaz Uddin, Ameer Khusro, Muhammad Umar Khayam Sahibzada, Márió Gajdács
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-12-01
coleção:	Microorganisms
Assuntos:	<i>Salmonella</i> Typhi H58 subtractive genomic analysis typhoid fever drug targets functional annotation XDR
Acesso em linha:	https://www.mdpi.com/2076-2607/9/12/2512
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