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How array design creates SNP ascertainment bias.

Single nucleotide polymorphisms (SNPs), genotyped with arrays, have become a widely used marker type in population genetic analyses over the last 10 years. However, compared to whole genome re-sequencing data, arrays are known to lack a substantial proportion of globally rare variants and tend to be...

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Autors principals: Johannes Geibel, Christian Reimer, Steffen Weigend, Annett Weigend, Torsten Pook, Henner Simianer
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2021-01-01
Col·lecció:PLoS ONE
Accés en línia:https://publications.goettingen-research-online.de/bitstream/2/85209/1/journal.pone.0245178.pdf
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