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The Inflammation in the Cytopathology of Patients With Mucopolysaccharidoses- Immunomodulatory Drugs as an Approach to Therapy

Mucopolysaccharidoses (MPS) are a group of lysosomal storage diseases (LSDs), characterized by the accumulation of glycosaminoglycans (GAGs). GAG storage-induced inflammatory processes are a driver of cytopathology in MPS and pharmacological immunomodulation can bring improvements in brain, cartilag...

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Principais autores: Anna-Maria Wiesinger, Brian Bigger, Roberto Giugliani, Maurizio Scarpa, Tobias Moser, Christina Lampe, Christoph Kampmann, Florian B. Lagler
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-05-01
Serier:Frontiers in Pharmacology
Fag:
mucopolysaccharidoses
MPS
immunomodulation
inflammation
cytopathology
drug discovery
Online adgang:https://www.frontiersin.org/articles/10.3389/fphar.2022.863667/full
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