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Extraordinary diversity of the CD28/CTLA4 family across jawed vertebrates

Members of the CD28 family are critical for the control of immune cell activation. While CD28 and CTLA4 were previously identified in teleost fish, most members of the CD28 family have been described only in tetrapods. Using a comparative genomics approach, we found (co)orthologs of all members of t...

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Principais autores: Sylvie M. A. Quiniou, Thomas Clark, Eva Bengtén, Jonathan P. Rast, Yuko Ohta, Martin Flajnik, Pierre Boudinot
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2024-11-01
coleção:Frontiers in Immunology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1501934/full
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