Endothelial, cytokine, and Th1/cellular host biomarkers discriminate complicated osteoarticular tuberculosis: a prospective single-center cohort study with ROC analysis

BackgroundOsteoarticular tuberculosis (OATB) accounts for 10–15% of extrapulmonary TB cases and causes progressive bone destruction, neurological compromise, and persistent disability. No validated host-based framework currently identifies patients at high risk of complicated disease course at basel...

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Autori principali:	Shuhrat Bozorov, Bakhtiyor Khamdamov, Isomiddin Usmanov, Nigora Faizullaeva, Musharraf Shodiyeva
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2026-05-01
Serie:	Frontiers in Cellular and Infection Microbiology
Soggetti:	endothelial dysfunction extrapulmonary tuberculosis host immunological biomarkers interferon-gamma osteoarticular tuberculosis prognostic stratification
Accesso online:	https://www.frontiersin.org/articles/10.3389/fcimb.2026.1866153/full
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