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A <it>Kallikrein 15 </it>(<it>KLK15</it>) single nucleotide polymorphism located close to a novel exon shows evidence of association with poor ovarian cancer survival

<p>Abstract</p> <p>Background</p> <p><it>KLK15 </it>over-expression is reported to be a significant predictor of reduced progression-free survival and overall survival in ovarian cancer. Our aim was to analyse the <it>KLK15 </it>gene for putative functional single nucleotide polymorphisms (SNPs) and...

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Principais autores: Song Honglin, Bolton Kelly L, Srinivasan Srilakshmi, Skeie Lene, Lose Felicity, Tan Olivia L, Dong Ying, Higgins Melanie, O'Mara Tracy, Nagle Christina M, Batra Jyotsna, Ramus Susan J, Gayther Simon A, Pharoah Paul DP, Kedda Mary-Anne, Spurdle Amanda B, Clements Judith A
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2011-04-01
Serier:BMC Cancer
Fag:
Kallikrein 15
single nucleotide polymorphisms
ovarian cancer
splice variants
Online adgang:http://www.biomedcentral.com/1471-2407/11/119
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